Medical Review and Validation
MD Calculator uses AI-assisted, source-verified validation to compare calculator logic against peer-reviewed primary sources and established clinical references.
Validated against primary sources by MD Calculator Clinical Validation (AI-assisted) · Last reviewed 2026-06-12
Review model
Validation checks formulas, input assumptions, unit handling, and displayed interpretations against cited source material.
No individual clinician is presented as the author or named reviewer of these pages. The review process is documented as organizational, AI-assisted source verification.
Clinical use
These calculators support professional judgment; they do not replace a clinician, local protocol, patient-specific assessment, or current guideline review.
Healthcare professionals should verify any result that could affect diagnosis, treatment, dosing, or disposition.
Sources and references
- MAP: Standard hemodynamic formula: MAP = DBP + (SBP - DBP) / 3.
- eGFR (CKD-EPI 2021): Inker LA, et al. New Creatinine- and Cystatin C-Based Equations to Estimate GFR without Race. N Engl J Med 2021;385:1737-1749.
- Creatinine Clearance: Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976;16:31-41.
- ASCVD 10-Year Risk: Goff DC, Lloyd-Jones DM, et al. 2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk (Pooled Cohort Equations). Circulation 2014;129(25 Suppl 2):S49-S73.
- BMI: World Health Organization. Body mass index (BMI) classification.
- Corrected Calcium: Payne RB, et al. Interpretation of serum calcium in patients with abnormal serum proteins. BMJ 1973;4:643-646.