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CrCl Calculator

The Creatinine Clearance calculator uses the Cockcroft-Gault equation to estimate renal function for medication dosing. It remains the gold standard for drug dose adjustments in many clinical settings.

Clinically reviewed

Calculator

Live
mg/dL

Normal: 0.7-1.3 mg/dL

years
kg

Use actual body weight

Enter values to see your result.

How to Use the Calculator

  1. Enter serum creatinine level.
  2. Enter patient age, weight, and sex.
  3. View creatinine clearance result instantly.

What the CrCl Result Means

Creatinine clearance estimates kidney function for drug dosing purposes. Normal CrCl is typically >90 mL/min. Lower values indicate reduced renal function and may require medication dose adjustments. Many drug labels specifically reference CrCl thresholds for dosing recommendations.

When to Use This Calculator

  • Dosing renally-cleared medications (e.g., vancomycin, aminoglycosides)
  • Adjusting anticoagulant doses (e.g., DOACs, enoxaparin)
  • Chemotherapy dose calculations
  • Contrast dye administration risk assessment

Frequently Asked Questions

When should I use CrCl vs eGFR?

Use CrCl (Cockcroft-Gault) when drug dosing guidelines specifically recommend it, as most pharmacokinetic studies used this equation. Use eGFR for CKD staging and disease monitoring.

Should I use actual or ideal body weight?

Use actual body weight in most cases. For obese patients (>130% ideal body weight), consider using adjusted body weight. For underweight patients, use actual weight to avoid overestimating renal function.

References & Guidelines